Hypericum Perforatum Extract

Synonyms:
St. John's Wort Extract
Hypericin, Pseudo-hypericin

Appearance: Dark Brown Fine Powder

Active ingredients:
Ｎaphthodianthrones (Hypericin, Pseudohypericin, Protohypericin, Protopseudohypericin etc.)

Specification:
0.3% Hypericins by UV
0.45% Hypericins by UV
0.5% Hypericins by UV
0.6% Hypericins by UV
0.75% Hypericins by UV
0.1% Hypericin by HPLC
0.2% Hypericin by HPLC
0.3% Hypericin by HPLC
0.45% Hypericin by HPLC
0.75% Hypericin by HPLC

We also have double standardized product as 0.45% Hypericins by UV, 0.2% Hypericin by HPLC

Introduction

Hypericum perforatum L. Hypericum perforatum, known as perforate St John's-wort, common Saint John’s wort and St John’s wort, is a flowering plant in the family Hypericaceae. Hypericum perforatum is native to parts of Europe and Asia but has spread to temperate regions worldwide as a cosmopolitan invasive weed

The whole herbal St. John’s Wort (Hypericum perforatum L.) contains:
1) naphthodianthrones: which are Hypericin, Pseudohypericin, Protohypericin, Protopseudohypericin, Cyclopseudohypericin, Isohypericin, Emodin-anthrone, Hypericode-hydrodianthrone etc.
２）Flavonoids: including Kampferol Luteolin, Myricetin, Quercetin, Quercitrin, Isoquercitrin, ３）Hyperin/Hyperoside etc.　Hyperforin substance: Hyperforin Adhyperforin etc.

The St. John's Wort Extract (also called as Hypericum Perforatum Extract) powder (Hypericins) is extracted from tips and tops in flowering or aerial parts, all our extracted are extracted by ethanol (food grade). Our material comes from a special producing area, which can guarantee the high quality to produce higher content of Hypericin.

Hypericin (Molecular Formula: C30H16O8, Molecular Weight: 504.43
CAS NO. 548-04-9)
is a naphthodianthrone, an anthraquinone derivative which, together with hyperforin, is one of the principal active constituents of Hypericum (Saint John's wort) Hypericin is believed to act as an antibiotic, antiviral and non-specific kinase inhibitor. Hypericin may inhibit the action of the enzyme dopamine β-hydroxylase, leading to increased dopamine levels, although thus possibly decreasing norepinephrine and epinephrine.

Application

1) Anti-depression effect
The hypericin, an active ingredient from the St. John’s Wort extract has Anti-depressive and sedative properties, it is an effective remedy for the nervous system, relaxing tension, and anxiety and lifting the spirits, Enhancing the effect of neurotransmitters in the brain, As a tissue restorative for nerves, St. John’s Wort is indicated for stroke patients, for mild neuroses, sleepwalkers, and accident victims. So it is usually used in tablet, capsule or oral liquid as medicine and also as an additive in functional or healthy food.

2) Anti-viral disease
The two ingredients Hypericin and Pseudohypericin directly act on viral disease.

3) Anti -Cancer

4) Anti-inflammatory
The bis-flavonoid in the St. John’s Wort can activate the hemameba to affect Anti-inflammatory.

5) Antibacterial
The Hyperforin substance has the property of Antibacterial to inhabit the growing of Staphylococcus aureus, Corynebacterium diphtheria, Antistaphylococcal Penicillins.

6) An excellent feed additive
The St. John’s Wort powder has a very good prevention and treatment for avian influenza, Swine fever, foot-and-mouth disease, and a strong Inhibition of Viral Replication by RNA Interference in Animals.

COA and Chromatogram For Reference

Hypericum Perforatum Extract